會員介紹

學經歷

現任職位

1. 臺大醫院泌尿部主任
2. 臺大醫院泌尿部主治醫師
3. 臺大醫學院泌尿科副教授

學歷

1. 臺大醫學系畢業(1976-1983)
2. 空軍醫官預官役(1983-1985)
3. 臺大泌尿部住院醫師(1985-1989)
4. 省立桃園醫院泌尿科主治醫師(1989-1995)
5. 美國紐約羅傑斯特大學醫學中心研究員(1998-1999)
6. 臺大醫院泌尿部主治醫師(1995-迄今)

執照及學會參與

執照

1. 泌尿科專科醫師
2. 外科專科醫師

學會

1. 臺灣泌尿科醫學會會員
2. 臺灣男性學醫學會會員
3. 臺灣醫學會會員

治療專長

1. 男性不孕
2. 前列腺疾病

榮譽獎勵

論文著作

英文學術論文

1. Chang HC, Chen S.C., Chen J, Hsieh JT. In vitro gene expression changes of androgen receptor coactivators after hormone deprivation in an androgen-dependent prostate cancer cell line. Journal of the Formosan Medical Association 2005; 104(9):652-658.
2. Ni J, Wen X, Yao J, Chang HC, Yin Y, Zhang M, Xie S, Chen M, Simons B, Chang P, di Sant'Agnese A, Messing EM, Yeh S. Tocopherol-Associated Protein Suppresses Prostate Cancer Cell Growth by Inhibition of the Phosphoinositide 3-Kinase Pathway. Cancer Res 2005; 65(21):9807-9816.
3. Wilfred C.H.Wu, Chen SC, Hsieh JT, Chen J, Chang HC. Penile tuberculosis associated with monoclonal gammopathy of undetermined significance. Journal of the Formosan Medical Association 2005.
4. Hsu CL, Chen YL, Ting HJ, Lin WJ, Yang Z, Zhang Y, Wang L, Wu CT, Chang HC, Yeh S, Pimplikar SW, Chang C. Androgen receptor (AR) NH2- and COOH-terminal interactions result in the differential influences on the AR-mediated transactivation and cell growth. Molecular Endocrinology 2005; 19(2):350-361.
5. Altuwaijri S, Lee DK, Chuang KH, Ting HJ, Yang Z, Xu Q, Tsai MY, Yeh S, Hanchett LA, Chang HC, Chang C. Androgen receptor regulates expression of skeletal muscle-specific proteins and muscle cell types. Endocrine 2004; 25(1):27-32.
6. Nishimura K, Ting HJ, Harada Y, Tokizane T, Nonomura N, Kang HY, Chang HC, Yeh S, Miyamoto H, Shin M, Aozasa K, Okuyama A, Chang C. Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator. Cancer Res 2003; 63(16):4888-4894.
7. Chen SU, Lien YR, Ko TM, Ho HN, Yang YS, Chang HC. Genetic screening of karyotypes and azoospermic factors for infertile men who are candidates for ICSI. Archives of Andrology 2003; 49(6):423-427.
8. Shieh JY, Chen SU, Wang YH, Chang HC, Ho HN, Yang YS. A protocol of electroejaculation and systematic assisted reproductive technology achieved high efficiency and efficacy for pregnancy for anejaculatory men with spinal cord injury. Archives of Physical Medicine & Rehabilitation 2003; 84(4):535-540.
9. Hsieh JT, Wong WY, Chen J, Chang HJ, Liu SP. Congenital isolated penile torsion in adults: untwist with plication. Urology 2002; 59(3):438-440.
10. Hsieh JT, Wong WY, Chang HJ, Chen J, Liu SP. One-stage correction of congenital complex penile curvature by tunica albuginea plications. Journal of the Formosan Medical Association 2002; 101(6):416-420.
11. Miyamoto H, Rahman M, Takatera H, Kang HY, Yeh S, Chang HC, Nishimura K, Fujimoto N, Chang C. A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth. Journal of Biological Chemistry 2002; 277(7):4609-4617.
12. Hsieh JT, Huang HE, Chen J, Chang HC, Liu SP. Modified plication of the tunica albuginea in treating congenital penile curvature. BJU International 2001; 88(3):236-240.
13. Sampson ER, Yeh SY, Chang HC, Tsai MY, Wang X, Ting HJ, Chang C. Identification and characterization of androgen receptor associated coregulators in prostate cancer cells. [Review] [54 refs]. Journal of Biological Regulators & Homeostatic Agents 2001; 15(2):123-129.
14. Yeh S, Sampson ER, Lee DK, Kim E, Hsu CL, Chen YL, Chang HC, Altuwaijri S, Huang KE, Chang C. Functional analysis of androgen receptor N-terminal and ligand binding domain interacting coregulators in prostate cancer. [Review] [54 refs]. Journal of the Formosan Medical Association 2000; 99(12):885-894.
15. Chen SU, Chen HF, Lien YR, Ho HN, Chang HC, Yang YS. Schedule to inject in vitro matured oocytes may increase pregnancy after intracytoplasmic sperm injection. Archives of Andrology 2000; 44(3):197-205.
16. Fujimoto N, Yeh S, Kang HY, Inui S, Chang HC, Mizokami A, Chang C. Cloning and characterization of androgen receptor coactivator, ARA55, in human prostate. Journal of Biological Chemistry 1999; 274(12):8316-8321.
17. Hsieh JT, Chang HC, Law HS, Shun CT. Cyst-like chylous coagulum in the urinary bladder of a patient with recurrent chyluria. Journal of the Formosan Medical Association 1999; 98(8):586-588.
18. Yeh S, Chang HC, Miyamoto H, Takatera H, Rahman M, Kang HY, Thin TH, Lin HK, Chang C. Differential induction of the androgen receptor transcriptional activity by selective androgen receptor coactivators. [Review] [40 refs]. Keio Journal of Medicine 1999; 48(2):87-92.
19. Yeh S, Kang HY, Miyamoto H, Nishimura K, Chang HC, Ting HJ, Rahman M, Lin HK, Fujimoto N, Hu YC, Mizokami A, Huang KE, Chang C. Differential induction of androgen receptor transactivation by different androgen receptor coactivators in human prostate cancer DU145 cells. Endocrine Journal 1999; 11(2):195-202.
20. Chang HC, Miyamoto H, Marwah P, Lardy H, Yeh S, Huang KE, Chang C. Suppression of Delta(5)-androstenediol-induced androgen receptor transactivation by selective steroids in human prostate cancer cells. Proceedings of the National Academy of Sciences of the United States of America 1999; 96(20):11173-11177.
21. Chang HC, Hsieh JT, Liu SP, Law HS, Chen SY, Yang YS. Fertilization capability of frozen epididymal sperm for intracytoplasmic sperm injection. Journal of the Formosan Medical Association 1999; 98(3):171-174.
22. Sung JF, Lin RS, Pu YS, Chen YC, Chang HC, Lai MK. Risk factors for prostate carcinoma in Taiwan: a case-control study in a Chinese population. Cancer 1999; 86(3):484-491.
23. Hsieh JT, Chang HC, Law HS, Hsieh CH, Cheng JT. In vivo evaluation of serotonergic agents and alpha-adrenergic blockers on premature ejaculation by inhibiting the seminal vesicle pressure response to electrical nerve stimulation. British Journal of Urology 1998; 82(2):237-240.
24. Chang HC, Chen SC, Hsieh JT, Shun CT, Lai MK. The effect of biological dyes and contrast media on the vas deferens in Long Evans rats. International Journal of Andrology 1998; 21(5):308-312.
25. Chen SU, Shieh JY, Wang YH, Chang HC, Ho HN, Yang YS. Pregnancy achieved by intracytoplasmic sperm injection using cryopreserved vasal-epididymal sperm from a man with spinal cord injury. Archives of Physical Medicine & Rehabilitation 1998; 79(2):218-221.
26. Jou HJ, Lien YR, Chang HC, Yang WJ, Hsieh ML, Ko TM. In vitro fertilization pregnancy achieved with epididymal caput sperm of a patient with obstructive azoospermia. Journal of the Formosan Medical Association 1995; 94(9):566-567.
27. Chang HC, Chang SC, Kuo HC, Tsai TC. Transrectal sonographic cystourethrography: studies in stress urinary incontinence. Urology 1990; 36(6):488-492.